Abstract The impact of the Antarctic Ozone Hole Influence over Southern Brazil in October 2015 was analyzed using daily mean data of the Total Column Ozone (TCO), Ultraviolet Index (UVI) and Radiative Cloud Fraction (RCF) from the Ozone Monitoring Instrument satellite instrument. Vertical profiles and fields of ozone content and Potential Vorticity available from the European Centre for Medium-Range Weather Forecast reanalysis, air masses backward trajectories from the HYbrid Single-Particle Lagrangian Integrated Trajectory model and channel 3 water vapor images from the Geostationary Operational Environmental Satellite GOES-13 were also analyzed. The five identified events showed an -7.4±2.3% average TCO reduction, leading to an +16.6±54.6% UVI increase even with a predominance of partly cloudy days. Other impacts were observed in the ozone profiles, where the most significant anomalies occurred from 650 K reaching 1.2 ppmv at the 850 K level. In the ozone fields at 700 K, the presence of a polar origin tongue was observed causing negatives anomalies between -0.2 and 0.4 ppmv in a transient system format forced with eastward-traveling Rossby waves passing through the Southern of Brazil and Uruguay.